Cilostazol is a vasodilator of the arteries that supply blood to the legs. It can also improve circulation by preventing platelets in the blood from clotting and sticking together. Cilostazol can treat symptoms of intermitten claudication, and may improve the ability to walk longer distances without pain.

Usually, cilostazol is taken twice a day on an empty stomach. Take at least 30 minutes before or 2 hours after breakfast or dinner. Take the drug the same time each day. Symptoms may not improve until up to 12 weeks. Contact your doctor if symptoms do not improve after 4 weeks.

Do not use if you have congestive heart failure. Alert your doctor of your medical history and other medications you take, especially if you smoke, have liver or kidney disease, or have heart disease. Many drugs can interact negatively with cilostazol. Inform your doctor if you become pregnant or breast-feed. Avoid grapefruit products.

Get emergency help if you suspect an allergic reaction or overdose. Contact your doctor immediately if you experience serious side effects, such as: chest pain, pounding heart, flu-like symptoms, lightheadedness, bloody urine or painful urination, shortness of breath, swelling in ankles or feet. Other side effects may include: abnormal bowel movements and digestive problems, runny nose, headache, and dizziness.